TIME (Tumor Immunity in the MicroEnvironment) classification based on tumor CD274 (PD-L1) expression status and tumor-infiltrating lymphocytes in colorectal carcinomas

Inhibitors targeting the PDCD1 (programmed cell death 1, PD-1) immune checkpoint pathway have revolutionized cancer treatment strategies. The TIME (Tumor Immunity in the MicroEnvironment) classification based on tumor CD274 (PDCD1 ligand 1, PD-L1) expression and tumor-infiltrating lymphocytes (TIL)...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Hamada, Tsuyoshi, Soong, Thing Rinda, Masugi, Yohei, Kosumi, Keisuke, Nowak, Jonathan A., da Silva, Annacarolina, Mu, Xinmeng Jasmine, Twombly, Tyler S., Koh, Hideo, Yang, Juhong, Song, Mingyang, Liu, Li, Gu, Mancang, Shi, Yan, Nosho, Katsuhiko, Morikawa, Teppei, Inamura, Kentaro, Shukla, Sachet A., Wu, Catherine J., Garraway, Levi A., Zhang, Xuehong, Wu, Kana, Meyerhardt, Jeffrey A., Chan, Andrew T., Glickman, Jonathan N., Rodig, Scott J., Freeman, Gordon J., Fuchs, Charles S., Nishihara, Reiko, Giannakis, Marios, Ogino, Shuji
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993482/
https://ncbi.nlm.nih.gov/pubmed/29900052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1442999
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