TIME (Tumor Immunity in the MicroEnvironment) classification based on tumor CD274 (PD-L1) expression status and tumor-infiltrating lymphocytes in colorectal carcinomas

Inhibitors targeting the PDCD1 (programmed cell death 1, PD-1) immune checkpoint pathway have revolutionized cancer treatment strategies. The TIME (Tumor Immunity in the MicroEnvironment) classification based on tumor CD274 (PDCD1 ligand 1, PD-L1) expression and tumor-infiltrating lymphocytes (TIL)...

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Detalles Bibliográficos
Publicado en:Oncoimmunology
Main Authors: Hamada, Tsuyoshi, Soong, Thing Rinda, Masugi, Yohei, Kosumi, Keisuke, Nowak, Jonathan A., da Silva, Annacarolina, Mu, Xinmeng Jasmine, Twombly, Tyler S., Koh, Hideo, Yang, Juhong, Song, Mingyang, Liu, Li, Gu, Mancang, Shi, Yan, Nosho, Katsuhiko, Morikawa, Teppei, Inamura, Kentaro, Shukla, Sachet A., Wu, Catherine J., Garraway, Levi A., Zhang, Xuehong, Wu, Kana, Meyerhardt, Jeffrey A., Chan, Andrew T., Glickman, Jonathan N., Rodig, Scott J., Freeman, Gordon J., Fuchs, Charles S., Nishihara, Reiko, Giannakis, Marios, Ogino, Shuji
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2018
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993482/
https://ncbi.nlm.nih.gov/pubmed/29900052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1442999
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