Tumor SQSTM1 (p62) expression and T cells in colorectal cancer

Evidence suggests that activation of autophagy in neoplastic cells potentiates antitumor immunity through cross-presentation of tumor-associated antigens to T cells and release of immune mediators. The SQSTM1 (sequestosome 1, p62) protein is degraded by activated autophagy, and might enhance immune...

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Publicado en:Oncoimmunology
Autores principales: Kosumi, Keisuke, Masugi, Yohei, Yang, Juhong, Qian, Zhi Rong, Kim, Sun A., Li, Wanwan, Shi, Yan, da Silva, Annacarolina, Hamada, Tsuyoshi, Liu, Li, Gu, Mancang, Twombly, Tyler S., Cao, Yin, Barbie, David A., Nosho, Katsuhiko, Baba, Hideo, Garrett, Wendy S., Meyerhardt, Jeffery A., Giovannucci, Edward L., Chan, Andrew T., Fuchs, Charles S., Ogino, Shuji, Nishihara, Reiko
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2017
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384412/
https://ncbi.nlm.nih.gov/pubmed/28405513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1284720
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