Tumor SQSTM1 (p62) expression and T cells in colorectal cancer

Evidence suggests that activation of autophagy in neoplastic cells potentiates antitumor immunity through cross-presentation of tumor-associated antigens to T cells and release of immune mediators. The SQSTM1 (sequestosome 1, p62) protein is degraded by activated autophagy, and might enhance immune...

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Vydáno v:Oncoimmunology
Hlavní autoři: Kosumi, Keisuke, Masugi, Yohei, Yang, Juhong, Qian, Zhi Rong, Kim, Sun A., Li, Wanwan, Shi, Yan, da Silva, Annacarolina, Hamada, Tsuyoshi, Liu, Li, Gu, Mancang, Twombly, Tyler S., Cao, Yin, Barbie, David A., Nosho, Katsuhiko, Baba, Hideo, Garrett, Wendy S., Meyerhardt, Jeffery A., Giovannucci, Edward L., Chan, Andrew T., Fuchs, Charles S., Ogino, Shuji, Nishihara, Reiko
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384412/
https://ncbi.nlm.nih.gov/pubmed/28405513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1284720
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