Cell Cycle Protein Expression in Neuroendocrine Tumors: Association of CDK4/CDK6, CCND1, and Phospho-RB1 With Proliferative Index

OBJECTIVES: Dysregulation of the cell cycle has been observed and implicated as an etiologic factor in a range of human malignancies, but remains relatively unstudied in neuroendocrine tumors (NETs). We evaluated expression of key proteins involved in cell cycle regulation, in a large cohort of NETs...

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Detalhes bibliográficos
Publicado no:Pancreas
Main Authors: Shi, Yan, Qian, Zhi Rong, Zhang, Sui, Li, Wanwan, Masugi, Yohei, Li, Tingting, Chan, Jennifer A., Yang, Juhong, Da Silva, Annacarolina, Gu, Mancang, Liu, Li, Hamada, Tsuyoshi, Kosumi, Keisuke, Dutton, Trevor, Brais, Lauren K., Nishihara, Reiko, Fuchs, Charles S., Ogino, Shuji, Kulke, Matthew H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645256/
https://ncbi.nlm.nih.gov/pubmed/28991877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000000944
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