MicroRNA MIR21 (miR-21) and PTGS2 expression in colorectal cancer and patient survival

PURPOSE: Prostaglandin-endoperoxide synthase 2 (PTGS2, cyclooxygenase-2; a target of aspirin) produces inflammatory mediator prostaglandin E(2) (PGE(2)), and contributes to colorectal neoplasia development. PTGS2-driven inflammatory responses can induce tumor expression of microRNA MIR21 (miR-21) th...

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書誌詳細
出版年:Clin Cancer Res
主要な著者: Mima, Kosuke, Nishihara, Reiko, Yang, Juhong, Dou, Ruoxu, Masugi, Yohei, Shi, Yan, da Silva, Annacarolina, Cao, Yin, Song, Mingyang, Nowak, Jonathan A., Gu, Mancang, Li, Wanwan, Morikawa, Teppei, Zhang, Xuehong, Wu, Kana, Baba, Hideo, Giovannucci, Edward L., Meyerhardt, Jeffrey A., Chan, Andrew T., Fuchs, Charles S., Qian, Zhi Rong, Ogino, Shuji
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970894/
https://ncbi.nlm.nih.gov/pubmed/26957558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2173
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