MicroRNA MIR21 and T cells in Colorectal Cancer

The complex interactions between colorectal neoplasia and immune cells in the tumor microenvironment remain to be elucidated. Experimental evidence suggests that microRNA MIR21 (miR-21) suppresses antitumor T-cell–mediated immunity. Thus, we hypothesized that tumor MIR21 expression might be inversel...

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Udgivet i:Cancer Immunol Res
Main Authors: Mima, Kosuke, Nishihara, Reiko, Nowak, Jonathan A., Kim, Sun A, Song, Mingyang, Inamura, Kentaro, Sukawa, Yasutaka, Masuda, Atsuhiro, Yang, Juhong, Dou, Ruoxu, Nosho, Katsuhiko, Baba, Hideo, Giovannucci, Edward L., Bowden, Michaela, Loda, Massimo, Giannakis, Marios, Bass, Adam J., Dranoff, Glenn, Freeman, Gordon J., Chan, Andrew T., Fuchs, Charles S., Qian, Zhi Rong, Ogino, Shuji
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703429/
https://ncbi.nlm.nih.gov/pubmed/26419959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-15-0084
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