MicroRNA MIR21 (miR-21) and PTGS2 expression in colorectal cancer and patient survival

PURPOSE: Prostaglandin-endoperoxide synthase 2 (PTGS2, cyclooxygenase-2; a target of aspirin) produces inflammatory mediator prostaglandin E(2) (PGE(2)), and contributes to colorectal neoplasia development. PTGS2-driven inflammatory responses can induce tumor expression of microRNA MIR21 (miR-21) th...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Mima, Kosuke, Nishihara, Reiko, Yang, Juhong, Dou, Ruoxu, Masugi, Yohei, Shi, Yan, da Silva, Annacarolina, Cao, Yin, Song, Mingyang, Nowak, Jonathan A., Gu, Mancang, Li, Wanwan, Morikawa, Teppei, Zhang, Xuehong, Wu, Kana, Baba, Hideo, Giovannucci, Edward L., Meyerhardt, Jeffrey A., Chan, Andrew T., Fuchs, Charles S., Qian, Zhi Rong, Ogino, Shuji
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970894/
https://ncbi.nlm.nih.gov/pubmed/26957558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2173
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