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MicroRNA MIR21 (miR-21) and PTGS2 expression in colorectal cancer and patient survival

PURPOSE: Prostaglandin-endoperoxide synthase 2 (PTGS2, cyclooxygenase-2; a target of aspirin) produces inflammatory mediator prostaglandin E(2) (PGE(2)), and contributes to colorectal neoplasia development. PTGS2-driven inflammatory responses can induce tumor expression of microRNA MIR21 (miR-21) th...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Mima, Kosuke, Nishihara, Reiko, Yang, Juhong, Dou, Ruoxu, Masugi, Yohei, Shi, Yan, da Silva, Annacarolina, Cao, Yin, Song, Mingyang, Nowak, Jonathan A., Gu, Mancang, Li, Wanwan, Morikawa, Teppei, Zhang, Xuehong, Wu, Kana, Baba, Hideo, Giovannucci, Edward L., Meyerhardt, Jeffrey A., Chan, Andrew T., Fuchs, Charles S., Qian, Zhi Rong, Ogino, Shuji
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970894/
https://ncbi.nlm.nih.gov/pubmed/26957558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2173
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