MicroRNA MIR21 (miR-21) and PTGS2 expression in colorectal cancer and patient survival

PURPOSE: Prostaglandin-endoperoxide synthase 2 (PTGS2, cyclooxygenase-2; a target of aspirin) produces inflammatory mediator prostaglandin E(2) (PGE(2)), and contributes to colorectal neoplasia development. PTGS2-driven inflammatory responses can induce tumor expression of microRNA MIR21 (miR-21) th...

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Bibliografske podrobnosti
izdano v:Clin Cancer Res
Main Authors: Mima, Kosuke, Nishihara, Reiko, Yang, Juhong, Dou, Ruoxu, Masugi, Yohei, Shi, Yan, da Silva, Annacarolina, Cao, Yin, Song, Mingyang, Nowak, Jonathan A., Gu, Mancang, Li, Wanwan, Morikawa, Teppei, Zhang, Xuehong, Wu, Kana, Baba, Hideo, Giovannucci, Edward L., Meyerhardt, Jeffrey A., Chan, Andrew T., Fuchs, Charles S., Qian, Zhi Rong, Ogino, Shuji
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970894/
https://ncbi.nlm.nih.gov/pubmed/26957558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2173
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