Fusobacterium nucleatum in Colorectal Cancer Relates to Immune Response Differentially by Tumor Microsatellite Instability Status

The presence of Fusobacterium nucleatum in colorectal carcinoma tissue has been associated with microsatellite instability (MSI), lower-level T-cell infiltrates, and poor clinical outcomes. Considering differences in the tumor-immune microenvironment of carcinomas with high or low MSI, we hypothesiz...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Hamada, Tsuyoshi, Zhang, Xuehong, Mima, Kosuke, Bullman, Susan, Sukawa, Yasutaka, Nowak, Jonathan A., Kosumi, Keisuke, Masugi, Yohei, Twombly, Tyler S., Cao, Yin, Song, Mingyang, Liu, Li, da Silva, Annacarolina, Shi, Yan, Gu, Mancang, Li, Wanwan, Koh, Hideo, Nosho, Katsuhiko, Inamura, Kentaro, Keum, NaNa, Wu, Kana, Meyerhardt, Jeffrey A., Kostic, Aleksandar D., Huttenhower, Curtis, Garrett, Wendy S., Meyerson, Matthew, Giovannucci, Edward L., Chan, Andrew T., Fuchs, Charles S., Nishihara, Reiko, Giannakis, Marios, Ogino, Shuji
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215508/
https://ncbi.nlm.nih.gov/pubmed/30228205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0174
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