Fusobacterium nucleatum in Colorectal Cancer Relates to Immune Response Differentially by Tumor Microsatellite Instability Status

The presence of Fusobacterium nucleatum in colorectal carcinoma tissue has been associated with microsatellite instability (MSI), lower-level T-cell infiltrates, and poor clinical outcomes. Considering differences in the tumor-immune microenvironment of carcinomas with high or low MSI, we hypothesiz...

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Gepubliceerd in:Cancer Immunol Res
Hoofdauteurs: Hamada, Tsuyoshi, Zhang, Xuehong, Mima, Kosuke, Bullman, Susan, Sukawa, Yasutaka, Nowak, Jonathan A., Kosumi, Keisuke, Masugi, Yohei, Twombly, Tyler S., Cao, Yin, Song, Mingyang, Liu, Li, da Silva, Annacarolina, Shi, Yan, Gu, Mancang, Li, Wanwan, Koh, Hideo, Nosho, Katsuhiko, Inamura, Kentaro, Keum, NaNa, Wu, Kana, Meyerhardt, Jeffrey A., Kostic, Aleksandar D., Huttenhower, Curtis, Garrett, Wendy S., Meyerson, Matthew, Giovannucci, Edward L., Chan, Andrew T., Fuchs, Charles S., Nishihara, Reiko, Giannakis, Marios, Ogino, Shuji
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215508/
https://ncbi.nlm.nih.gov/pubmed/30228205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0174
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