Non-proteinogenic amino acids in the pThr-2 position of a pentamer peptide that confer high binding affinity for the polo box domain (PBD) of polo-like kinase 1 (Plk1)

Por Qian, Wen-Jian, Park, Jung-Eun, Lee, Kyung S., Burke, Terrence R.
Publicado em 2012

Effects on Polo-like Kinase 1 Polo-box Domain Binding Affinities of Peptides Incurred by Structural Variation at the Phosphoamino Acid Position

Por Qian, Wenjian, Park, Jung-Eun, Liu, Fa, Lee, Kyung S., Burke, Terrence R.
Publicado em 2012

Probing Binding Modes of Small Molecule Inhibitors to the Polo-Box Domain of Human Polo-like Kinase 1

Por Liao, Chenzhong, Park, Jung-Eun, Bang, Jeong K., Nicklaus, Marc C., Lee, Kyung S.
Publicado em 2010

Synthesis and SAR of Thiazolylmethylphenyl Glucoside as Novel C-Aryl Glucoside SGLT2 Inhibitors

Por Song, Kwang-Seop, Lee, Suk Ho, Kim, Min Ju, Seo, Hee Jeong, Lee, Junwon, Lee, Sung-Han, Jung, Myung Eun, Son, Eun-Jung, Lee, MinWoo, Kim, Jeongmin, Lee, Jinhwa
Publicado em 2010

Optimizing Thiadiazole Analogues of Resveratrol vs. Three Chemopreventive Targets

Por Mayhoub, Abdelrahman S., Marler, Laura, Kondratyuk, Tamara, Park, Eun-Jung, Pezzuto, John M., Cushman, Mark
Publicado em 2011

Optimization of Thiazole Analogues of Resveratrol for Induction of NAD(P)H:quinone Reductase 1 (QR1)

Por Mayhoub, Abdelrahman S., Marler, Laura, Kondratyuk, Tamara P., Park, Eun-Jung, Pezzuto, John M., Cushman, Mark
Publicado em 2012

Structure-activity relationships and docking studies of synthetic 2-arylindole derivatives determined with aromatase and quinone reductase 1

Por Prior, Allan M., Yu, Xufen, Park, Eun-Jung, Kondratyuk, Tamara P., Lin, Yan, Pezzuto, John M., Sun, Dianqing
Publicado no Bioorg Med Chem Lett (2017)

Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents

Por Shen, Li, Park, Eun-Jung, Kondratyuk, Tamara P., Guendisch, Daniela, Marler, Laura, Pezzuto, John M., Wright, Anthony D., Sun, Dianqing
Publicado em 2011

Selective Synthesis and Biological Evaluation of Sulfate-Conjugated Resveratrol Metabolites

Por Hoshino, Juma, Park, Eun-Jung, Kondratyuk, Tamara P., Marler, Laura, Pezzuto, John M., van Breemen, Richard B., Mo, Shunyan, Li, Yongchao, Cushman, Mark
Publicado em 2010

Potential Chemopreventive Agents Based on the Structure of the Lead Compound 2-Bromo-1-hydroxyphenazine, Isolated from Streptomyces sp., Strain CNS284

Por Conda-Sheridan, Martin, Marler, Laura, Park, Eun-Jung, Kondratyuk, Tamara P., Jermihov, Katherine, Mesecar, Andrew D., Pezzuto, John M., Asolkar, Ratnakar N., Fenical, William, Cushman, Mark
Publicado em 2010

Identification, Synthesis, and Biological Evaluation of the Metabolites of 3-Amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36), a Promising Rexinoid Lea...

Por Chen, Lian, Conda-Sheridan, Martin, Narasimha Reddy, P. V., Morrell, Andrew, Park, Eun-Jung, Kondratyuk, Tamara P., Pezzuto, John M., van Breemen, Richard B., Cushman, Mark
Publicado em 2012

A POTENT AND SELECTIVE INHIBITOR TARGETING HUMAN AND MURINE 12/15-LOX

Por Armstrong, Michelle M., Freedman, Cody J., Jung, Joo Eun, Zheng, Yi, Kalyanaraman, Chakrapani, Jacobson, Matthew P., Simeonov, Anton, Maloney, David J., van Leyen, Klaus, Jadhav, Ajit, Holman, Theodore R.
Publicado no Bioorg Med Chem (2016)

Sendai F/HN Viroplexes for Efficient Transfection of Leukemic T Cells

Por Kim, Jung Seok, Lee, Yeon Kyung, Jeong, Hwa Yeon, Kang, Seong Jae, Kim, Min Woo, Ryu, Seung Hyun, Kim, Hong Sung, Kim, Keun Sik, Kim, Dong-Eun, Park, Yong Serk
Publicado em 2013

Design, Synthesis, and Biological Evaluation of Indenoisoquinoline Rexinoids with Chemopreventive Potential

Por Conda-Sheridan, Martin, Park, Eun-Jung, Beck, Daniel E., Narasimha Reddy, P. V., Nguyen, Trung X., Hu, Bingjie, Chen, Lian, White, Jerry J., van Breemen, Richard B., Pezzuto, John M., Cushman, Mark
Publicado em 2013

Tat-DJ-1 inhibits oxidative stress-mediated RINm5F cell death through suppression of NF-κB and MAPK activation

Por Jo, Hyo Sang, Cha, Hyun Ju, Kim, Sang Jin, Yeo, Hyeon Ji, Cho, Su Bin, Park, Jung Hwan, Lee, Chi Hern, Yeo, Eun Ji, Choi, Yeon Joo, Eum, Won Sik, Choi, Soo Young
Publicado no Med Chem Res (2016)

Potent and Selective Inhibitors of Human Reticulocyte 12/15-Lipoxygenase as Anti-Stroke Therapies

Por Rai, Ganesha, Joshi, Netra, Jung, Joo Eun, Liu, Yu, Schultz, Lena, Yasgar, Adam, Perry, Steve, Diaz, Giovanni, Zhang, Qiangli, Kenyon, Victor, Jadhav, Ajit, Simeonov, Anton, Lo, Eng H., van Leyen, Klaus, Maloney, David J., Holman, Theodore R.
Publicado em 2014

Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi

Por Brand, Stephen, Ko, Eun Jung, Viayna, Elisabet, Thompson, Stephen, Spinks, Daniel, Thomas, Michael, Sandberg, Lars, Francisco, Amanda F., Jayawardhana, Shiromani, Smith, Victoria C., Jansen, Chimed, De Rycker, Manu, Thomas, John, MacLean, Lorna, Osuna-Cabello, Maria, Riley, Jennifer, Scullion, Paul, Stojanovski, Laste, Simeons, Frederick R. C., Epemolu, Ola, Shishikura, Yoko, Crouch, Sabrinia D., Bakshi, Tania S., Nixon, Christopher J., Reid, Iain H., Hill, Alan P., Underwood, Tim Z., Hindley, Sean J., Robinson, Sharon A., Kelly, John M., Fiandor, Jose M., Wyatt, Paul G., Marco, Maria, Miles, Timothy J., Read, Kevin D., Gilbert, Ian H.
Publicado no J Med Chem (2017)