A POTENT AND SELECTIVE INHIBITOR TARGETING HUMAN AND MURINE 12/15-LOX

Human reticulocyte 12/15-Lipoxygenase (h12/15-LOX) is a lipid-oxidizing enzyme that can directly oxidize lipid membranes in the absence of a phospholipase, leading to a direct attack on organelles, such as the mitochondria. This cytotoxic activity of h12/15-LOX is up-regulated in neurons and endothe...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Armstrong, Michelle M., Freedman, Cody J., Jung, Joo Eun, Zheng, Yi, Kalyanaraman, Chakrapani, Jacobson, Matthew P., Simeonov, Anton, Maloney, David J., van Leyen, Klaus, Jadhav, Ajit, Holman, Theodore R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778748/
https://ncbi.nlm.nih.gov/pubmed/26899595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.01.042
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados