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Discovery of Potent and Selective Inhibitors of Human Reticulocyte 15- Lipoxygenase-1
There are a variety of lipoxygenases in the human body (hLO), each having a distinct role in cellular biology. Human reticulocyte 15-Lipoxygenase-1 (15-hLO-1), which catalyzes the dioxygenation of 1,4-cis,cis-pentadiene-containing polyunsaturated fatty acids, is implicated in a number of diseases in...
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| Hlavní autoři: | , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2966298/ https://ncbi.nlm.nih.gov/pubmed/20866075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm1008852 |
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