Discovery of Potent and Selective Inhibitors of Human Reticulocyte 15- Lipoxygenase-1

There are a variety of lipoxygenases in the human body (hLO), each having a distinct role in cellular biology. Human reticulocyte 15-Lipoxygenase-1 (15-hLO-1), which catalyzes the dioxygenation of 1,4-cis,cis-pentadiene-containing polyunsaturated fatty acids, is implicated in a number of diseases in...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Rai, Ganesha, Kenyon, Victor, Jadhav, Ajit, Schultz, Lena, Armstrong, Michelle, Jameson, J Brian, Hoobler, Eric, Leister, William, Simeonov, Anton, Holman, Theodore R., Maloney, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966298/
https://ncbi.nlm.nih.gov/pubmed/20866075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm1008852
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky