Tat-DJ-1 inhibits oxidative stress-mediated RINm5F cell death through suppression of NF-κB and MAPK activation

Oxidative stress is highly involved in the development of diabetes mellitus by destruction of pancreatic β-cells. DJ-1 is an antioxidant protein and DJ-1 expression levels are known to be reduced in diabetes mellitus. Thus, we examined the effects of DJ-1 protein against oxidative stress-induced pan...

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Опубликовано в: :Med Chem Res
Главные авторы: Jo, Hyo Sang, Cha, Hyun Ju, Kim, Sang Jin, Yeo, Hyeon Ji, Cho, Su Bin, Park, Jung Hwan, Lee, Chi Hern, Yeo, Eun Ji, Choi, Yeon Joo, Eum, Won Sik, Choi, Soo Young
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2016
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075024/
https://ncbi.nlm.nih.gov/pubmed/27818604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-016-1698-4
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