Mitochondrial inhibitor as a new class of insulin sensitizer

Por Zhang, Yong, Ye, Jianping
Publicado em 2012

Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states

Por Yan, Yan, Zhou, X. Edward, Novick, Scott J., Shaw, Simon J., Li, Yingwu, Brunzelle, Joseph S., Hitoshi, Yasumichi, Griffin, Patrick R., Xu, H. Eric, Melcher, Karsten
Publicado no J Biol Chem (2019)

Fetuin B aggravates liver X receptor-mediated hepatic steatosis through AMPK in HepG2 cells and mice

Por Zhou, Wenjing, Yang, Ji, Zhu, Jinzhou, Wang, Yuming, Wu, Yue, Xu, Liqian, Yang, Yunmei
Publicado no Am J Transl Res (2019)

Spinal AMP kinase activity differentially regulates phrenic motor plasticity

Por Perim, Raphael Rodrigues, Fields, Daryl P., Mitchell, Gordon S.
Publicado no J Appl Physiol (1985) (2020)

CaMKK2 Suppresses Muscle Regeneration through the Inhibition of Myoblast Proliferation and Differentiation

Por Ye, Cheng, Zhang, Duo, Zhao, Lei, Li, Yan, Yao, Xiaohan, Wang, Hui, Zhang, Shengjie, Liu, Wei, Cao, Hongchao, Yu, Shuxian, Wang, Yucheng, Jiang, Jingjing, Wang, Hui, Li, Xihua, Ying, Hao
Publicado no Int J Mol Sci (2016)

Counteracting Roles of AMP Deaminase and AMP Kinase in the Development of Fatty Liver

Por Lanaspa, Miguel A., Cicerchi, Christina, Garcia, Gabriela, Li, Nanxing, Roncal-Jimenez, Carlos A., Rivard, Christopher J., Hunter, Brandi, Andrés-Hernando, Ana, Ishimoto, Takuji, Sánchez-Lozada, Laura G., Thomas, Jeffrey, Hodges, Robert S., Mant, Colin T., Johnson, Richard J.
Publicado em 2012

Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders

Por Viollet, Benoit, Foretz, Marc, Guigas, Bruno, Horman, Sandrine, Dentin, Renaud, Bertrand, Luc, Hue, Louis, Andreelli, Fabrizio
Publicado em 2006

The endotoxemia cardiac dysfunction is attenuated by AMPK/mTOR signaling pathway regulating autophagy

Por Zhang, Jie, Zhao, Peng, Quan, Nanhu, Wang, Lin, Chen, Xu, Cates, Courtney, Rousselle, Thomas, Li, Ji
Publicado no Biochem Biophys Res Commun (2017)

AMPK mediates inhibition of electrolyte transport and NKCC1 activity by reactive oxygen species

Por King, Stephanie J., Bunz, Michael, Chappell, Alfred, Scharl, Michael, Docherty, Michael, Jung, Barbara, Lytle, Christian, McCole, Declan F.
Publicado no Am J Physiol Gastrointest Liver Physiol (2019)

Cells Lacking the Fumarase Tumor Suppressor Are Protected from Apoptosis through a Hypoxia-Inducible Factor-Independent, AMPK-Dependent Mechanism

Por Bardella, Chiara, Olivero, Martina, Lorenzato, Annalisa, Geuna, Massimo, Adam, Julie, O'Flaherty, Linda, Rustin, Pierre, Tomlinson, Ian, Pollard, Patrick J., Di Renzo, Maria Flavia
Publicado em 2012

Metabolic sensor AMPK directly phosphorylates RAG1 protein and regulates V(D)J recombination

Por Um, Jee-Hyun, Brown, Alexandra L., Singh, Samarendra K., Chen, Yong, Gucek, Marjan, Lee, Baeck-Seung, Luckey, Megan A., Kim, Myung K., Park, Jung-Hyun, Sleckman, Barry P., Gellert, Martin, Chung, Jay H.
Publicado em 2013

AMPK attenuates microtubule proliferation in cardiac hypertrophy

Por Fassett, John T., Hu, Xinli, Xu, Xin, Lu, Zhongbing, Zhang, Ping, Chen, Yingjie, Bache, Robert J.
Publicado em 2013

Caspase cleavage and nuclear retention of the energy sensor AMPK-α1 during apoptosis

Por Anees Rahman Cheratta, Faisal Thayyullathil, Simon A. Hawley, Fiona A. Ross, Abdelmajdid Atrih, Douglas J. Lamont, Siraj Pallichankandy, Karthikeyan Subburayan, Ameer Alakkal, Rachid Rezgui, Alex Gray, D. Grahame Hardie, Sehamuddin Galadari
Publicado em 2022-05-01

Human muscle fibre type-specific regulation of AMPK and downstream targets by exercise

Por Kristensen, Dorte E, Albers, Peter H, Prats, Clara, Baba, Otto, Birk, Jesper B, Wojtaszewski, Jørgen F P
Publicado no J Physiol (2015)

Structural basis of AMPK regulation by small molecule activators

Por Xiao, Bing, Sanders, Matthew J., Carmena, David, Bright, Nicola J., Haire, Lesley F., Underwood, Elizabeth, Patel, Bhakti R., Heath, Richard B., Walker, Philip A., Hallen, Stefan, Giordanetto, Fabrizio, Martin, Stephen R., Carling, David, Gamblin, Steven J.
Publicado em 2013

Nuclear translocation of AMPK-α1 potentiates striatal neurodegeneration in Huntington’s disease

Por Ju, Tz-Chuen, Chen, Hui-Mei, Lin, Jiun-Tsai, Chang, Ching-Pang, Chang, Wei-Cheng, Kang, Jheng-Jie, Sun, Cheng-Pu, Tao, Mi-Hua, Tu, Pang-Hsien, Chang, Chen, Dickson, Dennis W., Chern, Yijuang
Publicado em 2011

Proteolytic cleavage of AMPKα and intracellular MMP9 expression are both required for TLR4-mediated mTORC1 activation and HIF-1α expression in leukocytes

Por Zhang, Zhiyong, Amorosa, Louis F., Coyle, Susette M., Macor, Marie A., Lubitz, Sara E., Carson, Jeffrey L., Birnbaum, Morris J., Lee, Leonard Y., Haimovich, Beatrice
Publicado no J Immunol (2015)

CCL2 Is a Negative Regulator of AMP-Activated Protein Kinase to Sustain mTOR Complex-1 Activation...

Por Roca, Hernan, Varsos, Zachary S, Pienta, Kenneth J
Publicado em 2009

Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade

Por Sanders, Matthew J., Grondin, Pascal O., Hegarty, Bronwyn D., Snowden, Michael A., Carling, David
Publicado em 2007

Paraoxonase 2 facilitates pancreatic cancer growth and metastasis by stimulating GLUT1-mediated glucose transport

Por Nagarajan, Arvindhan, Dogra, Shaillay Kumar, Sun, Lisha, Gandotra, Neeru, Ho, Thuy, Cai, Guoping, Cline, Gary, Kumar, Priti, Cowles, Robert A., Wajapeyee, Narendra
Publicado no Mol Cell (2017)