Paraoxonase 2 facilitates pancreatic cancer growth and metastasis by stimulating GLUT1-mediated glucose transport

Metabolic deregulation is a hallmark of human cancers, and the glycolytic and glutamine metabolism pathways were shown to be deregulated in pancreatic ductal adenocarcinoma (PDAC). To identify new metabolic regulators of PDAC tumor growth and metastasis, we systematically knocked down metabolic gene...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Nagarajan, Arvindhan, Dogra, Shaillay Kumar, Sun, Lisha, Gandotra, Neeru, Ho, Thuy, Cai, Guoping, Cline, Gary, Kumar, Priti, Cowles, Robert A., Wajapeyee, Narendra
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567863/
https://ncbi.nlm.nih.gov/pubmed/28803777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.07.014
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