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Paraoxonase 2 facilitates pancreatic cancer growth and metastasis by stimulating GLUT1-mediated glucose transport
Metabolic deregulation is a hallmark of human cancers, and the glycolytic and glutamine metabolism pathways were shown to be deregulated in pancreatic ductal adenocarcinoma (PDAC). To identify new metabolic regulators of PDAC tumor growth and metastasis, we systematically knocked down metabolic gene...
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Pubblicato in: | Mol Cell |
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Autori principali: | , , , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2017
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5567863/ https://ncbi.nlm.nih.gov/pubmed/28803777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.07.014 |
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