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AMPK attenuates microtubule proliferation in cardiac hypertrophy

Cell hypertrophy requires increased protein synthesis and expansion of the cytoskeletal networks that support cell enlargement. AMPK limits anabolic processes, such as protein synthesis, when energy supply is insufficient, but its role in cytoskeletal remodeling is not known. Here, we examined the i...

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Detalhes bibliográficos
Main Authors: Fassett, John T., Hu, Xinli, Xu, Xin, Lu, Zhongbing, Zhang, Ping, Chen, Yingjie, Bache, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602754/
https://ncbi.nlm.nih.gov/pubmed/23316058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00935.2011
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