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Adenosine Kinase attenuates cardiomyocyte microtubule stabilization and protects against pressure overload-induced hypertrophy and LV dysfunction

Adenosine exerts numerous protective actions in the heart, including attenuation of cardiac hypertrophy. Adenosine kinase (ADK) converts adenosine to adenosine monophosphate (AMP) and is the major route of myocardial adenosine metabolism, however, the impact of ADK activity on cardiac structure and...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Fassett, John, Xu, Xin, Kwak, Dongmin, Zhu, Guangshuo, Fassett, Erin K, Zhang, Ping, Wang, Huan, Mayer, Bernd, Bache, Robert J., Chen, Yingjie
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6555768/
https://ncbi.nlm.nih.gov/pubmed/30910669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2019.03.015
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