Microtubule Actin Cross-Linking Factor 1 Regulates Cardiomyocyte Microtubule Distribution and Adaptation to Hemodynamic Overload

Aberrant cardiomyocyte microtubule growth is a feature of pressure overload induced cardiac hypertrophy believed to contribute to left ventricular (LV) dysfunction. Microtubule Actin Cross-linking Factor 1 (MACF1/Acf7) is a 600 kd spectraplakin that stabilizes and guides microtubule growth along act...

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Bibliographic Details
Main Authors: Fassett, John T., Xu, Xin, Kwak, Dongmin, Wang, Huan, Liu, Xiaoyu, Hu, Xinli, Bache, Robert J., Chen, Yingjie
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784444/
https://ncbi.nlm.nih.gov/pubmed/24086300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073887
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