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Double Stranded RNA–Dependent Protein Kinase Deficiency Protects the Heart from Systolic Overload-Induced Congestive Heart Failure
BACKGROUND: Double stranded RNA–dependent protein kinase (PKR) is a eukaryotic initiation factor 2α kinase that inhibits mRNA translation under stress conditions. PKR also mediates inflammatory and apoptotic signaling independent of translational regulation. Congestive heart failure (CHF) is associa...
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| Asıl Yazarlar: | , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3972332/ https://ncbi.nlm.nih.gov/pubmed/24463368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.113.002209 |
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