Xanthine Oxidase Inhibition with Febuxostat Attenuates Systolic Overload-induced Left Ventricular Hypertrophy and Dysfunction in Mice

The purine analog xanthine oxidase (XO) inhibitors (XOIs), allopurinol and oxypurinol, have been reported to protect against heart failure secondary to myocardial infarction or rapid ventricular pacing. Since these agents might influence other aspects of purine metabolism that could influence their...

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Detalhes bibliográficos
Main Authors: Xu, Xin, Hu, Xinli, Lu, Zhongbing, Zhang, Ping, Zhao, Lin, Wessale, Jerry L., Bache, Robert J., Chen, Yingjie
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610415/
https://ncbi.nlm.nih.gov/pubmed/18995179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cardfail.2008.06.006
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