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Xanthine Oxidase Inhibition with Febuxostat Attenuates Systolic Overload-induced Left Ventricular Hypertrophy and Dysfunction in Mice

The purine analog xanthine oxidase (XO) inhibitors (XOIs), allopurinol and oxypurinol, have been reported to protect against heart failure secondary to myocardial infarction or rapid ventricular pacing. Since these agents might influence other aspects of purine metabolism that could influence their...

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Bibliografische gegevens
Hoofdauteurs: Xu, Xin, Hu, Xinli, Lu, Zhongbing, Zhang, Ping, Zhao, Lin, Wessale, Jerry L., Bache, Robert J., Chen, Yingjie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610415/
https://ncbi.nlm.nih.gov/pubmed/18995179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cardfail.2008.06.006
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