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Mitochondrial inhibitor as a new class of insulin sensitizer
Insulin resistance is a major risk factor for type 2 diabetes. AMP-activated protein kinase (AMPK) is a drug target in the improvement of insulin sensitivity. Several insulin-sensitizing medicines are able to activate AMPK through inhibition of mitochondrial functions. These drugs, such as metformin...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3660979/ https://ncbi.nlm.nih.gov/pubmed/23710432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2012.06.010 |
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