The endotoxemia cardiac dysfunction is attenuated by AMPK/mTOR signaling pathway regulating autophagy

AMP-activated protein kinase (AMPK), an enzyme that plays a role in cellular energy homeostasis, modulates myocardial signaling in the heart. Myocardial dysfunction is a common complication of sepsis. Autophagy is involved in the aging related cardiac dysfunction. However, the role of AMPK in sepsis...

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Vydáno v:Biochem Biophys Res Commun
Hlavní autoři: Zhang, Jie, Zhao, Peng, Quan, Nanhu, Wang, Lin, Chen, Xu, Cates, Courtney, Rousselle, Thomas, Li, Ji
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593793/
https://ncbi.nlm.nih.gov/pubmed/28807827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.08.034
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