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mTOR attenuates the inflammatory response in cardiomyocytes and prevents cardiac dysfunction in pathological hypertrophy

Previous studies have suggested that inhibition of the mammalian target of rapamycin (mTOR) by rapamycin suppresses myocardial hypertrophy. However, the role of mTOR in the progression of cardiac dysfunction in pathological hypertrophy has not been fully defined. Interestingly, recent reports indica...

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Bibliographic Details
Main Authors: Song, Xiaoxiao, Kusakari, Yoichiro, Xiao, Chun-Yang, Kinsella, Stuart D., Rosenberg, Michael A., Scherrer-Crosbie, Marielle, Hara, Kenta, Rosenzweig, Anthony, Matsui, Takashi
Format: Artigo
Language:Inglês
Published: American Physiological Society 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006320/
https://ncbi.nlm.nih.gov/pubmed/20861467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00338.2010
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