mTOR attenuates the inflammatory response in cardiomyocytes and prevents cardiac dysfunction in pathological hypertrophy

Previous studies have suggested that inhibition of the mammalian target of rapamycin (mTOR) by rapamycin suppresses myocardial hypertrophy. However, the role of mTOR in the progression of cardiac dysfunction in pathological hypertrophy has not been fully defined. Interestingly, recent reports indica...

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Detalhes bibliográficos
Main Authors: Song, Xiaoxiao, Kusakari, Yoichiro, Xiao, Chun-Yang, Kinsella, Stuart D., Rosenberg, Michael A., Scherrer-Crosbie, Marielle, Hara, Kenta, Rosenzweig, Anthony, Matsui, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Receptors and Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006320/
https://ncbi.nlm.nih.gov/pubmed/20861467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00338.2010
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