Cardiac mTOR protects the heart against ischemia-reperfusion injury

Cardiac mammalian target of rapamycin (mTOR) is necessary and sufficient to prevent cardiac dysfunction in pathological hypertrophy. However, the role of cardiac mTOR in heart failure after ischemic injury remains undefined. To address this question, we used transgenic (Tg) mice with cardiac-specifi...

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Detalhes bibliográficos
Main Authors: Aoyagi, Toshinori, Kusakari, Yoichiro, Xiao, Chun-Yang, Inouye, Brendan T., Takahashi, Masaya, Scherrer-Crosbie, Marielle, Rosenzweig, Anthony, Hara, Kenta, Matsui, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Signaling and Stress Response
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404649/
https://ncbi.nlm.nih.gov/pubmed/22561297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00241.2012
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