Cardiac mTOR protects the heart against ischemia-reperfusion injury

Cardiac mammalian target of rapamycin (mTOR) is necessary and sufficient to prevent cardiac dysfunction in pathological hypertrophy. However, the role of cardiac mTOR in heart failure after ischemic injury remains undefined. To address this question, we used transgenic (Tg) mice with cardiac-specifi...

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Main Authors: Aoyagi, Toshinori, Kusakari, Yoichiro, Xiao, Chun-Yang, Inouye, Brendan T., Takahashi, Masaya, Scherrer-Crosbie, Marielle, Rosenzweig, Anthony, Hara, Kenta, Matsui, Takashi
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Physiological Society 2012
Ábhair:
Signaling and Stress Response
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404649/
https://ncbi.nlm.nih.gov/pubmed/22561297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00241.2012
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