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Cardiac mTOR protects the heart against ischemia-reperfusion injury

Cardiac mammalian target of rapamycin (mTOR) is necessary and sufficient to prevent cardiac dysfunction in pathological hypertrophy. However, the role of cardiac mTOR in heart failure after ischemic injury remains undefined. To address this question, we used transgenic (Tg) mice with cardiac-specifi...

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Autors principals: Aoyagi, Toshinori, Kusakari, Yoichiro, Xiao, Chun-Yang, Inouye, Brendan T., Takahashi, Masaya, Scherrer-Crosbie, Marielle, Rosenzweig, Anthony, Hara, Kenta, Matsui, Takashi
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404649/
https://ncbi.nlm.nih.gov/pubmed/22561297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00241.2012
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