Cardiac mTOR rescues the detrimental effects of diet-induced obesity in the heart after ischemia-reperfusion

Diet-induced obesity deteriorates the recovery of cardiac function after ischemia-reperfusion (I/R) injury. While mechanistic target of rapamycin (mTOR) is a key mediator of energy metabolism, the effects of cardiac mTOR in ischemic injury under metabolic syndrome remains undefined. Using cardiac-sp...

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Udgivet i:Am J Physiol Heart Circ Physiol
Main Authors: Aoyagi, Toshinori, Higa, Jason K., Aoyagi, Hiroko, Yorichika, Naaiko, Shimada, Briana K., Matsui, Takashi
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2015
Fag:
Signaling and Stress Response
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469881/
https://ncbi.nlm.nih.gov/pubmed/25888508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00008.2015
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