The Role of Diacylglycerol Kinase ζ and Phosphatidic Acid in the Mechanical Activation of Mammalian Target of Rapamycin (mTOR) Signaling and Skeletal Muscle Hypertrophy

The activation of mTOR signaling is essential for mechanically induced changes in skeletal muscle mass, and previous studies have suggested that mechanical stimuli activate mTOR (mammalian target of rapamycin) signaling through a phospholipase D (PLD)-dependent increase in the concentration of phosp...

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Dettagli Bibliografici
Autori principali: You, Jae-Sung, Lincoln, Hannah C., Kim, Chan-Ran, Frey, John W., Goodman, Craig A., Zhong, Xiao-Ping, Hornberger, Troy A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894336/
https://ncbi.nlm.nih.gov/pubmed/24302719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.531392
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