The Role of Diacylglycerol Kinase ζ and Phosphatidic Acid in the Mechanical Activation of Mammalian Target of Rapamycin (mTOR) Signaling and Skeletal Muscle Hypertrophy

The activation of mTOR signaling is essential for mechanically induced changes in skeletal muscle mass, and previous studies have suggested that mechanical stimuli activate mTOR (mammalian target of rapamycin) signaling through a phospholipase D (PLD)-dependent increase in the concentration of phosp...

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Hlavní autoři: You, Jae-Sung, Lincoln, Hannah C., Kim, Chan-Ran, Frey, John W., Goodman, Craig A., Zhong, Xiao-Ping, Hornberger, Troy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894336/
https://ncbi.nlm.nih.gov/pubmed/24302719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.531392
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