Intramolecular Hydrogen Bond Expectations in Medicinal Chemistry

Por Giordanetto, Fabrizio, Tyrchan, Christian, Ulander, Johan
Publicado no ACS Med Chem Lett (2017)

Stapled Vasoactive Intestinal Peptide (VIP) Derivatives Improve VPAC(2) Agonism and Glucose-Dependent Insulin Secretion

Por Giordanetto, Fabrizio, Revell, Jefferson D., Knerr, Laurent, Hostettler, Marie, Paunovic, Amalia, Priest, Claire, Janefeldt, Annika, Gill, Adrian
Publicado em 2013

Discovery of AZD2716: A Novel Secreted Phospholipase A(2) (sPLA(2)) Inhibitor for the Treatment of Coronary Artery Disease

Por Giordanetto, Fabrizio, Pettersen, Daniel, Starke, Ingemar, Nordberg, Peter, Dahlström, Mikael, Knerr, Laurent, Selmi, Nidhal, Rosengren, Birgitta, Larsson, Lars-Olof, Sandmark, Jenny, Castaldo, Marie, Dekker, Niek, Karlsson, Ulla, Hurt-Camejo, Eva
Publicado no ACS Med Chem Lett (2016)

Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties

Por Over, Björn, McCarren, Patrick, Artursson, Per, Foley, Michael, Giordanetto, Fabrizio, Grönberg, Gunnar, Hilgendorf, Constanze, Lee, Maurice D., Matsson, Pär, Muncipinto, Giovanni, Pellisson, Mélanie, Perry, Matthew W. D., Svensson, Richard, Duvall, Jeremy R., Kihlberg, Jan
Publicado em 2014

Structural basis of AMPK regulation by small molecule activators

Por Xiao, Bing, Sanders, Matthew J., Carmena, David, Bright, Nicola J., Haire, Lesley F., Underwood, Elizabeth, Patel, Bhakti R., Heath, Richard B., Walker, Philip A., Hallen, Stefan, Giordanetto, Fabrizio, Martin, Stephen R., Carling, David, Gamblin, Steven J.
Publicado em 2013

Design of Selective sPLA(2)-X Inhibitor (−)-2-{2-[Carbamoyl-6-(trifluoromethoxy)-1H-indol-1-yl]pyridine-2-yl}propanoic Acid

Por Giordanetto, Fabrizio, Knerr, Laurent, Nordberg, Peter, Pettersen, Daniel, Selmi, Nidhal, Beisel, Hans-Georg, de la Motte, Hannah, Månsson, Åsa, Dahlström, Mikael, Broddefalk, Johan, Saarinen, Gabrielle, Klingegård, Fredrik, Hurt-Camejo, Eva, Rosengren, Birgitta, Wikström, Johannes, Wågberg, Maria, Brengdahl, Johan, Rohman, Mattias, Sandmark, Jenny, Åkerud, Tomas, Roth, Robert G., Jansen, Frank, Ahlqvist, Marie
Publicado no ACS Med Chem Lett (2018)

Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A(2) Type X (sPLA(2)-X) Inhibitors

Por Knerr, Laurent, Giordanetto, Fabrizio, Nordberg, Peter, Pettersen, Daniel, Selmi, Nidhal, Beisel, Hans-Georg, de la Motte, Hannah, Olsson, Thomas, Perkins, Tim D. J., Herslöf, Margareta, Månsson, Åsa, Dahlström, Mikael, Starke, Ingemar, Broddefalk, Johan, Saarinen, Gabrielle, Klingegård, Fredrik, Hurt-Camejo, Eva, Rosengren, Birgitta, Brengdahl, Johan, Jansen, Frank, Rohman, Mattias, Sandmark, Jenny, Hallberg, Kenth, Åkerud, Tomas, Roth, Robert G., Ahlqvist, Marie
Publicado no ACS Med Chem Lett (2018)