Cryo-EM structure of the activated RET signaling complex reveals the importance of its cysteine-rich domain

Por Bigalke, Janna M., Aibara, Shintaro, Roth, Robert, Dahl, Göran, Gordon, Euan, Dorbéus, Sarah, Amunts, A., Sandmark, Jenny
Publicado no Sci Adv (2019)

Structural analysis identifies an escape route from the adverse lipogenic effects of liver X receptor ligands

Por Belorusova, Anna Y., Evertsson, Emma, Hovdal, Daniel, Sandmark, Jenny, Bratt, Emma, Maxvall, Ingela, Schulman, Ira G., Åkerblad, Peter, Lindstedt, Eva-Lotte
Publicado no Commun Biol (2019)

Structure and biophysical characterization of the human full-length neurturin–GFRa2 complex: A role for heparan sulfate in signaling

Por Sandmark, Jenny, Dahl, Göran, Öster, Linda, Xu, Bingze, Johansson, Patrik, Akerud, Tomas, Aagaard, Anna, Davidsson, Pia, Bigalke, Janna M., Winzell, Maria Sörhede, Rainey, G. Jonah, Roth, Robert G.
Publicado no J Biol Chem (2018)

Discovery of AZD2716: A Novel Secreted Phospholipase A(2) (sPLA(2)) Inhibitor for the Treatment of Coronary Artery Disease

Por Giordanetto, Fabrizio, Pettersen, Daniel, Starke, Ingemar, Nordberg, Peter, Dahlström, Mikael, Knerr, Laurent, Selmi, Nidhal, Rosengren, Birgitta, Larsson, Lars-Olof, Sandmark, Jenny, Castaldo, Marie, Dekker, Niek, Karlsson, Ulla, Hurt-Camejo, Eva
Publicado no ACS Med Chem Lett (2016)

Creating Novel Activated Factor XI Inhibitors through Fragment Based Lead Generation and Structure Aided Drug Design

Por Fjellström, Ola, Akkaya, Sibel, Beisel, Hans-Georg, Eriksson, Per-Olof, Erixon, Karl, Gustafsson, David, Jurva, Ulrik, Kang, Daiwu, Karis, David, Knecht, Wolfgang, Nerme, Viveca, Nilsson, Ingemar, Olsson, Thomas, Redzic, Alma, Roth, Robert, Sandmark, Jenny, Tigerström, Anna, Öster, Linda
Publicado no PLoS One (2015)

Design of Selective sPLA(2)-X Inhibitor (−)-2-{2-[Carbamoyl-6-(trifluoromethoxy)-1H-indol-1-yl]pyridine-2-yl}propanoic Acid

Por Giordanetto, Fabrizio, Knerr, Laurent, Nordberg, Peter, Pettersen, Daniel, Selmi, Nidhal, Beisel, Hans-Georg, de la Motte, Hannah, Månsson, Åsa, Dahlström, Mikael, Broddefalk, Johan, Saarinen, Gabrielle, Klingegård, Fredrik, Hurt-Camejo, Eva, Rosengren, Birgitta, Wikström, Johannes, Wågberg, Maria, Brengdahl, Johan, Rohman, Mattias, Sandmark, Jenny, Åkerud, Tomas, Roth, Robert G., Jansen, Frank, Ahlqvist, Marie
Publicado no ACS Med Chem Lett (2018)

Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A(2) Type X (sPLA(2)-X) Inhibitors

Por Knerr, Laurent, Giordanetto, Fabrizio, Nordberg, Peter, Pettersen, Daniel, Selmi, Nidhal, Beisel, Hans-Georg, de la Motte, Hannah, Olsson, Thomas, Perkins, Tim D. J., Herslöf, Margareta, Månsson, Åsa, Dahlström, Mikael, Starke, Ingemar, Broddefalk, Johan, Saarinen, Gabrielle, Klingegård, Fredrik, Hurt-Camejo, Eva, Rosengren, Birgitta, Brengdahl, Johan, Jansen, Frank, Rohman, Mattias, Sandmark, Jenny, Hallberg, Kenth, Åkerud, Tomas, Roth, Robert G., Ahlqvist, Marie
Publicado no ACS Med Chem Lett (2018)

Identification and analyses of inhibitors targeting apolipoprotein(a) kringle domains KIV-7, KIV-10, and KV provide insight into kringle domain function

Por Sandmark, Jenny, Tigerström, Anna, Akerud, Tomas, Althage, Magnus, Antonsson, Thomas, Blaho, Stefan, Bodin, Cristian, Boström, Jonas, Chen, Yantao, Dahlén, Anders, Eriksson, Per-Olof, Evertsson, Emma, Fex, Tomas, Fjellström, Ola, Gustafsson, David, Herslöf, Margareta, Hicks, Ryan, Jarkvist, Emelie, Johansson, Carina, Kalies, Inge, Karlsson Svalstedt, Birgitta, Kartberg, Fredrik, Legnehed, Anne, Martinsson, Sofia, Moberg, Andreas, Ridderström, Marianne, Rosengren, Birgitta, Sabirsh, Alan, Thelin, Anders, Vinblad, Johanna, Wellner, Annika U., Xu, Bingze, Östlund-Lindqvist, Ann-Margret, Knecht, Wolfgang
Publicado no J Biol Chem (2020)