An investigation into pharmaceutically relevant mutagenicity data and the influence on Ames predictive potential

ανά McCarren, Patrick, Springer, Clayton, Whitehead, Lewis
Έκδοση 2011

Origins of Regioselectivity and Alkene-Directing Effects in Nickel-Catalyzed Reductive Couplings of Alkynes and Aldehydes

ανά Liu, Peng, McCarren, Patrick, Cheong, Paul Ha-Yeon, Jamison, Timothy F., Houk, K. N.
Έκδοση 2010

Nitrosonium-Catalyzed Decomposition of S-Nitrosothiols in Solution: A Theoretical and Experimental Study

ανά Zhao, Yi-Lei, McCarren, Patrick R., Houk, K. N., Choi, Bo Yoon, Toone, Eric J.
Έκδοση 2005

Allosteric inhibitors of Mycobacterium tuberculosis tryptophan synthase

ανά Michalska, Karolina, Chang, Changsoo, Maltseva, Natalia I., Jedrzejczak, Robert, Robertson, Gregory T., Gusovsky, Fabian, McCarren, Patrick, Schreiber, Stuart L., Nag, Partha P., Joachimiak, Andrzej
Τόπος έκδοσης Protein Sci (2020)

The Autophagy-Related Beclin-1 Protein Requires the Coiled-Coil and BARA Domains To Form a Homodimer with Submicromolar Affinity

ανά Ranaghan, Matthew J., Durney, Michael A., Mesleh, Michael F., McCarren, Patrick R., Garvie, Colin W., Daniels, Douglas S., Carey, Kimberly L., Skepner, Adam P., Levine, Beth, Perez, Jose R.
Τόπος έκδοσης Biochemistry (2017)

Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties

ανά Over, Björn, McCarren, Patrick, Artursson, Per, Foley, Michael, Giordanetto, Fabrizio, Grönberg, Gunnar, Hilgendorf, Constanze, Lee, Maurice D., Matsson, Pär, Muncipinto, Giovanni, Pellisson, Mélanie, Perry, Matthew W. D., Svensson, Richard, Duvall, Jeremy R., Kihlberg, Jan
Έκδοση 2014

The Drug Repurposing Hub: a next-generation drug library and information resource

ανά Corsello, Steven M., Bittker, Joshua A., Liu, Zihan, Gould, Joshua, McCarren, Patrick, Hirschman, Jodi E., Johnston, Stephen E., Vrcic, Anita, Wong, Bang, Khan, Mariya, Asiedu, Jacob, Narayan, Rajiv, Mader, Christopher C., Subramanian, Aravind, Golub, Todd R.
Τόπος έκδοσης Nat Med (2017)

Targeted Covalent Inhibition of Plasmodium FK506 Binding Protein 35

ανά Atack, Thomas C., Raymond, Donald D., Blomquist, Christa A., Pasaje, Charisse Flerida, McCarren, Patrick R., Moroco, Jamie, Befekadu, Henock B., Robinson, Foxy P., Pal, Debjani, Esherick, Lisl Y., Ianari, Alessandra, Niles, Jacquin C., Sellers, William R.
Τόπος έκδοσης ACS Med Chem Lett (2020)

A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase

ανά Wellington, Samantha, Nag, Partha P, Michalska, Karolina, Johnston, Stephen E, Jedrzejczak, Robert P, Kaushik, Virendar K, Clatworthy, Anne E, Siddiqi, Noman, McCarren, Patrick, Bajrami, Besnik, Maltseva, Natalia I, Combs, Senya, Fisher, Stewart L, Joachimiak, Andrzej, Schreiber, Stuart L, Hung, Deborah T
Τόπος έκδοσης Nat Chem Biol (2017)

Single Diastereomer of a Macrolactam Core Binds Specifically to Myeloid Cell Leukemia 1 (MCL1)

ανά Fang, Chao, D’Souza, Brendan, Thompson, Christopher F., Clifton, Matthew C., Fairman, James W., Fulroth, Ben, Leed, Alison, McCarren, Patrick, Wang, Lili, Wang, Yikai, Feau, Clementine, Kaushik, Virendar K., Palmer, Michelle, Wei, Guo, Golub, Todd R., Hubbard, Brian K., Serrano-Wu, Michael H.
Τόπος έκδοσης ACS Med Chem Lett (2014)

An Unbiased Approach To Identify Endogenous Substrates of “Histone” Deacetylase 8

ανά Olson, David E., Udeshi, Namrata D., Wolfson, Noah A., Pitcairn, Carol Ann, Sullivan, Eric D., Jaffe, Jacob D., Svinkina, Tanya, Natoli, Ted, Lu, Xiaodong, Paulk, Joshiawa, McCarren, Patrick, Wagner, Florence F., Barker, Doug, Howe, Eleanor, Lazzaro, Fanny, Gale, Jennifer P., Zhang, Yan-Ling, Subramanian, Aravind, Fierke, Carol A., Carr, Steven A., Holson, Edward B.
Έκδοση 2014