Crystal structure of MICU2 and comparison with MICU1 reveal insights into the uniporter gating mechanism

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JNK1 Phosphorylates SIRT1 and Promotes Its Enzymatic Activity

od Nasrin, Nargis, Kaushik, Virendar K., Fortier, Eric, Wall, Daniel, Pearson, Kevin J., de Cabo, Rafael, Bordone, Laura
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Point mutations at the catalytic site of PCSK9 inhibit folding, autoprocessing, and interaction with the LDL receptor

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A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase

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Izdano u Nat Chem Biol (2017)

Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease

od Leshchiner, Elizaveta S., Rush, Jason S., Durney, Michael A., Cao, Zhifang, Dančík, Vlado, Chittick, Benjamin, Wu, Huixian, Petrone, Adam, Bittker, Joshua A., Phillips, Andrew, Perez, Jose R., Shamji, Alykhan F., Kaushik, Virendar K., Daly, Mark J., Graham, Daniel B., Schreiber, Stuart L., Xavier, Ramnik J.
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Single Diastereomer of a Macrolactam Core Binds Specifically to Myeloid Cell Leukemia 1 (MCL1)

od Fang, Chao, D’Souza, Brendan, Thompson, Christopher F., Clifton, Matthew C., Fairman, James W., Fulroth, Ben, Leed, Alison, McCarren, Patrick, Wang, Lili, Wang, Yikai, Feau, Clementine, Kaushik, Virendar K., Palmer, Michelle, Wei, Guo, Golub, Todd R., Hubbard, Brian K., Serrano-Wu, Michael H.
Izdano u ACS Med Chem Lett (2014)

Genetic Analysis in UK Biobank Links Insulin Resistance and Transendothelial Migration Pathways to Coronary Artery Disease

od Klarin, Derek, Zhu, Qiuyu Martin, Emdin, Connor A., Chaffin, Mark, Horner, Steven, McMillan, Brian J., Leed, Alison, Weale, Michael E., Spencer, Chris C. A., Aguet, François, Segrè, Ayellet V., Ardlie, Kristin G., Khera, Amit V., Kaushik, Virendar K., Natarajan, Pradeep, Consortium, CARDIoGRAMplusC4D, Kathiresan, Sekar
Izdano u Nat Genet (2017)

Multimodal small-molecule screening for human prion protein binders

od Reidenbach, Andrew G., Mesleh, Michael F., Casalena, Dominick, Vallabh, Sonia M., Dahlin, Jayme L., Leed, Alison J., Chan, Alix I., Usanov, Dmitry L., Yehl, Jenna B., Lemke, Christopher T., Campbell, Arthur J., Shah, Rishi N., Shrestha, Om K., Sacher, Joshua R., Rangel, Victor L., Moroco, Jamie A., Sathappa, Murugappan, Nonato, Maria Cristina, Nguyen, Kong T., Wright, S. Kirk, Liu, David R., Wagner, Florence F., Kaushik, Virendar K., Auld, Douglas S., Schreiber, Stuart L., Minikel, Eric Vallabh
Izdano u J Biol Chem (2020)