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A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase
New antibiotics with novel targets are greatly needed. Bacteria have numerous essential functions, but only a small fraction of such processes—primarily those involved in macromolecular synthesis—are inhibited by current drugs. Targeting metabolic enzymes has been the focus of recent interest, but e...
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| Wydane w: | Nat Chem Biol |
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| Główni autorzy: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2017
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6886523/ https://ncbi.nlm.nih.gov/pubmed/28671682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2420 |
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