Strategies for the synthesis of the novel antitumor agent peloruside A

par Williams, David R, Nag, Partha P, Zorn, Nicolas
Publié 2008

Allosteric inhibitors of Mycobacterium tuberculosis tryptophan synthase

par Michalska, Karolina, Chang, Changsoo, Maltseva, Natalia I., Jedrzejczak, Robert, Robertson, Gregory T., Gusovsky, Fabian, McCarren, Patrick, Schreiber, Stuart L., Nag, Partha P., Joachimiak, Andrzej
Publié dans Protein Sci (2020)

Identification of novel inhibitors of non-replicating Mycobacterium tuberculosis using a carbon starvation model

par Grant, Sarah Schmidt, Kawate, Tomohiko, Nag, Partha P., Silvis, Melanie R., Gordon, Katherine, Stanley, Sarah A., Kazyanskaya, Ed, Nietupski, Ray, Golas, Aaron, Fitzgerald, Michael, Cho, Sanghyun, Franzblau, Scott G., Hung, Deborah T.
Publié 2013

A substrate-driven allosteric switch that enhances PDI catalytic activity

par Bekendam, Roelof H., Bendapudi, Pavan K., Lin, Lin, Nag, Partha P., Pu, Jun, Kennedy, Daniel R., Feldenzer, Alexandra, Chiu, Joyce, Cook, Kristina M., Furie, Bruce, Huang, Mingdong, Hogg, Philip J., Flaumenhaft, Robert
Publié dans Nat Commun (2016)

ML212: A small-molecule probe for investigating fluconazole resistance mechanisms in Candida albicans

par Youngsaye, Willmen, Hartland, Cathy L, Morgan, Barbara J, Ting, Amal, Nag, Partha P, Vincent, Benjamin, Mosher, Carrie A, Bittker, Joshua A, Dandapani, Sivaraman, Palmer, Michelle, Whitesell, Luke, Lindquist, Susan, Schreiber, Stuart L, Munoz, Benito
Publié 2013

Discovery of bisamide-heterocycles as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake

par Dockendorff, Chris, Faloon, Patrick W., Germain, Andrew, Yu, Miao, Youngsaye, Willmen, Nag, Partha P., Bennion, Melissa, Penman, Marsha, Nieland, Thomas J. F., Dandapani, Sivaraman, Perez, José R., Munoz, Benito, Palmer, Michelle A., Schreiber, Stuart L., Krieger, Monty
Publié dans Bioorg Med Chem Lett (2015)

Conservation of the structure and function of bacterial tryptophan synthases

par Michalska, Karolina, Gale, Jennifer, Joachimiak, Grazyna, Chang, Changsoo, Hatzos-Skintges, Catherine, Nocek, Boguslaw, Johnston, Stephen E., Bigelow, Lance, Bajrami, Besnik, Jedrzejczak, Robert P., Wellington, Samantha, Hung, Deborah T., Nag, Partha P., Fisher, Stewart L., Endres, Michael, Joachimiak, Andrzej
Publié dans IUCrJ (2019)

A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase

par Wellington, Samantha, Nag, Partha P, Michalska, Karolina, Johnston, Stephen E, Jedrzejczak, Robert P, Kaushik, Virendar K, Clatworthy, Anne E, Siddiqi, Noman, McCarren, Patrick, Bajrami, Besnik, Maltseva, Natalia I, Combs, Senya, Fisher, Stewart L, Joachimiak, Andrzej, Schreiber, Stuart L, Hung, Deborah T
Publié dans Nat Chem Biol (2017)

Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies

par Dockendorff, Chris, Nagiec, Marek M., Weïwer, Michel, Buhrlage, Sara, Ting, Amal, Nag, Partha P., Germain, Andrew, Kim, Han-Je, Youngsaye, Willmen, Scherer, Christina, Bennion, Melissa, Xue, Linlong, Stanton, Benjamin Z., Lewis, Timothy A., MacPherson, Lawrence, Palmer, Michelle, Foley, Michael A., Perez, José R., Schreiber, Stuart L.
Publié 2012

Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI)-Mediated Lipid Transport

par Dockendorff, Chris, Faloon, Patrick W., Yu, Miao, Youngsaye, Willmen, Penman, Marsha, Nieland, Thomas J. F., Nag, Partha P., Lewis, Timothy A., Pu, Jun, Bennion, Melissa, Negri, Joseph, Paterson, Conor, Lam, Garrett, Dandapani, Sivaraman, Perez, José R., Munoz, Benito, Palmer, Michelle A., Schreiber, Stuart L., Krieger, Monty
Publié dans ACS Med Chem Lett (2015)

Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes

par Sharabi, Kfir, Lin, Hua, Tavares, Clint D. J., Dominy, John E., Camporez, Joao Paulo, Perry, Rachel J., Schilling, Roger, Rines, Amy K., Lee, Jaemin, Hickey, Marc, Bennion, Melissa, Palmer, Michelle, Nag, Partha P., Bittker, Joshua A., Perez, José, Jedrychowski, Mark P., Ozcan, Umut, Gygi, Steve P., Kamenecka, Theodore M., Shulman, Gerald I., Schreiber, Stuart L., Griffin, Patrick R., Puigserver, Pere
Publié dans Cell (2017)

Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis

par Rossmann, Marlies P., Hoi, Karen, Chan, Victoria, Abraham, Brian J., Yang, Song, Mullahoo, James, Papanastasiou, Malvina, Wang, Ying, Elia, Ilaria, Perlin, Julie R., Hagedorn, Elliott J., Hetzel, Sara, Weigert, Raha, Vyas, Sejal, Nag, Partha P., Sullivan, Lucas B., Warren, Curtis R., Dorjsuren, Bilguujin, Greig, Eugenia Custo, Adatto, Isaac, Cowan, Chad A., Schreiber, Stuart L., Young, Richard A., Meissner, Alexander, Haigis, Marcia C., Hekimi, Siegfried, Carr, Steven A., Zon, Leonard I.
Publié dans Science (2021)