Structural Principles in the Development of Cyclic Peptidic Enzyme Inhibitors

Tekijä Xu, Peng, Andreasen, Peter A., Huang, Mingdong
Julkaisussa Int J Biol Sci (2017)

Challenges for drug discovery - a case study of urokinase receptor inhibition

Tekijä Chen, Zhuo, Lin, Lin, Huai, Qing, Huang, Mingdong
Julkaistu 2009

Expression and crystallographic studies of the ligand-binding region of the human endocytic collagen receptor uPARAP

Tekijä Yuan, Cai, Huang, Joy He, Liu, Min, Huang, Mingdong
Julkaisussa Acta Crystallogr F Struct Biol Commun (2015)

Structure-based Engineering of Species Selectivity in the Interaction between Urokinase and Its Receptor: IMPLICATION FOR PRECLINICAL CANCER THERAPY

Tekijä Lin, Lin, Gårdsvoll, Henrik, Huai, Qing, Huang, Mingdong, Ploug, Michael
Julkaistu 2010

Recombinant hepatocyte growth factor activator inhibitor 1: expression in Drosophila S2 cells, purification and crystallization

Tekijä Liu, Min, Yuan, Cai, Jiang, Yunbin, Jiang, Longguang, Huang, Mingdong
Julkaisussa Acta Crystallogr F Struct Biol Commun (2017)

Be Active or Not: the Relative Contribution of Active and Passive Tumor Targeting of Nanomaterials

Tekijä Li, Rui, Zheng, Ke, Yuan, Cai, Chen, Zhuo, Huang, Mingdong
Julkaisussa Nanotheranostics (2017)

Novel pH-sensitive zinc phthalocyanine assembled with albumin for tumor targeting and treatment

Tekijä Wang, Ying, Zheng, Ke, Xuan, Guangshan, Huang, Mingdong, Xue, Jinping
Julkaisussa Int J Nanomedicine (2018)

Crystal structure, epitope, and functional impact of an antibody against a superactive FVIIa provide insights into allosteric mechanism

Tekijä Jiang, Longguang, Xie, Xie, Li, Jinyu, Persson, Egon, Huang, Mingdong
Julkaisussa Res Pract Thromb Haemost (2019)

Crystal Structure of the Bovine Lactadherin C2 Domain, a Membrane Binding Motif, Shows Similarity to the C2 Domains of Factor V and Factor VIII

Tekijä Lin, Lin, Huai, Qing, Huang, Mingdong, Furie, Bruce, Furie, Barbara C.
Julkaistu 2007

A fluorescent fatty acid probe, DAUDA, selectively displaces two myristates bound in human serum albumin

Tekijä Wang, Yu, Luo, Zhipu, Shi, Xiaoli, Wang, Huan, Nie, Lei, Huang, Mingdong
Julkaistu 2011

Structural Mechanism of Ring-opening Reaction of Glucose by Human Serum Albumin

Tekijä Wang, Yu, Yu, Haiyang, Shi, Xiaoli, Luo, Zhipu, Lin, Donghai, Huang, Mingdong
Julkaistu 2013

Therapeutics targeting the fibrinolytic system

Tekijä Lin, Haili, Xu, Luning, Yu, Shujuan, Hong, Wanjin, Huang, Mingdong, Xu, Peng
Julkaisussa Exp Mol Med (2020)

X-ray sequence and crystal structure of luffaculin 1, a novel type 1 ribosome-inactivating protein

Tekijä Hou, Xiaomin, Chen, Minghuang, Chen, Liqing, Meehan, Edward J, Xie, Jieming, Huang, Mingdong
Julkaistu 2007

Mimicry of the Regulatory Role of Urokinase in Lamellipodia Formation by Introduction of a Non-native Interdomain Disulfide Bond in Its Receptor

Tekijä Gårdsvoll, Henrik, Kjaergaard, Magnus, Jacobsen, Benedikte, Kriegbaum, Mette C., Huang, Mingdong, Ploug, Michael
Julkaistu 2011

Receptor-Targeting Phthalocyanine Photosensitizer for Improving Antitumor Photocytotoxicity

Tekijä Xu, Peng, Chen, Jincan, Chen, Zhuo, Zhou, Shanyong, Hu, Ping, Chen, Xueyuan, Huang, Mingdong
Julkaistu 2012

Crystal Structures of Matriptase in Complex with Its Inhibitor Hepatocyte Growth Factor Activator Inhibitor-1

Tekijä Zhao, Baoyu, Yuan, Cai, Li, Rui, Qu, Dan, Huang, Mingdong, Ngo, Jacky Chi Ki
Julkaistu 2013

A Perspective on Reagent Diversity and Non-covalent Binding of Reactive Carbonyl Species (RCS) and Effector Reagents in Non-enzymatic Glycation (NEG): Mechanistic Considerations an...

Tekijä Rodnick, Kenneth J., Holman, R. W., Ropski, Pamela S., Huang, Mingdong, Swislocki, Arthur L. M.
Julkaisussa Front Chem (2017)

Crystal Structure of the Michaelis Complex between Tissue-type Plasminogen Activator and Plasminogen Activators Inhibitor-1

Tekijä Gong, Lihu, Liu, Min, Zeng, Tu, Shi, Xiaoli, Yuan, Cai, Andreasen, Peter A., Huang, Mingdong
Julkaisussa J Biol Chem (2015)

Structural basis of specific inhibition of tissue-type plasminogen activator by plasminogen activators inhibitor-1

Tekijä Gong, Lihu, Liu, Min, Zeng, Tu, Shi, Xiaoli, Yuan, Cai, Andreasen, Peter A., Huang, Mingdong
Julkaisussa Data Brief (2016)

The crystal structure of a multidomain protease inhibitor (HAI-1) reveals the mechanism of its auto-inhibition

Tekijä Liu, Min, Yuan, Cai, Jensen, Jan K., Zhao, Baoyu, Jiang, Yunbin, Jiang, Longguang, Huang, Mingdong
Julkaisussa J Biol Chem (2017)