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Structural basis of specific inhibition of tissue-type plasminogen activator by plasminogen activators inhibitor-1
Thrombosis is a leading cause of death worldwide [1]. Recombinant tissue-type plasminogen activator (tPA) is the FDA-approved thrombolytic drug for ischemic strokes, myocardial infarction and pulmonary embolism. tPA is a multi-domain serine protease of the trypsin-family [2] and catalyses the critic...
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| Publicado no: | Data Brief |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731420/ https://ncbi.nlm.nih.gov/pubmed/26909366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dib.2015.12.050 |
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