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Crystal Structures of Matriptase in Complex with Its Inhibitor Hepatocyte Growth Factor Activator Inhibitor-1

Matriptase, a type II trans-membrane serine protease of the S1 trypsin-like family, is expressed on the surface of nearly all normal human epithelium and found in biological fluid-like human milk. Matriptase overexpression has been implicated in tumor progression in certain epithelium-derived cancer...

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Detalhes bibliográficos
Main Authors: Zhao, Baoyu, Yuan, Cai, Li, Rui, Qu, Dan, Huang, Mingdong, Ngo, Jacky Chi Ki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630853/
https://ncbi.nlm.nih.gov/pubmed/23443661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.454611
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