High-affinity Cyclic Peptide Matriptase Inhibitors

The type II transmembrane serine protease matriptase is a key activator of multiple signaling pathways associated with cell proliferation and modification of the extracellular matrix. Deregulated matriptase activity correlates with a number of diseases, including cancer and hence highly selective ma...

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Detalhes bibliográficos
Main Authors: Quimbar, Pedro, Malik, Uru, Sommerhoff, Christian P., Kaas, Quentin, Chan, Lai Y., Huang, Yen-Hua, Grundhuber, Maresa, Dunse, Kerry, Craik, David J., Anderson, Marilyn A., Daly, Norelle L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650424/
https://ncbi.nlm.nih.gov/pubmed/23548907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.460030
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