Crystal Structures of Cholesteryl Ester Transfer Protein in Complex with Inhibitors

Human plasma cholesteryl ester transfer protein (CETP) transports cholesteryl ester from the antiatherogenic high-density lipoproteins (HDL) to the proatherogenic low-density and very low-density lipoproteins (LDL and VLDL). Inhibition of CETP has been shown to raise human plasma HDL cholesterol (HD...

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Autores principales: Liu, Shenping, Mistry, Anil, Reynolds, Jennifer M., Lloyd, David B., Griffor, Matthew C., Perry, David A., Ruggeri, Roger B., Clark, Ronald W., Qiu, Xiayang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Protein Structure and Folding
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481329/
https://ncbi.nlm.nih.gov/pubmed/22961980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.380063
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