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Mimicry of the Regulatory Role of Urokinase in Lamellipodia Formation by Introduction of a Non-native Interdomain Disulfide Bond in Its Receptor

The high-affinity interaction between the urokinase-type plasminogen activator (uPA) and its glycolipid-anchored receptor (uPAR) plays a regulatory role for both extravascular fibrinolysis and uPAR-mediated adhesion and migration on vitronectin-coated surfaces. We have recently proposed that the adh...

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Detalhes bibliográficos
Main Authors: Gårdsvoll, Henrik, Kjaergaard, Magnus, Jacobsen, Benedikte, Kriegbaum, Mette C., Huang, Mingdong, Ploug, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234840/
https://ncbi.nlm.nih.gov/pubmed/22025616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.300020
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