Conformational Regulation of Urokinase Receptor Function: IMPACT OF RECEPTOR OCCUPANCY AND EPITOPE-MAPPED MONOCLONAL ANTIBODIES ON LAMELLIPODIA INDUCTION

The urokinase-type plasminogen activator receptor (uPAR) is a glycolipid-anchored membrane protein with an established role in focalizing uPA-mediated plasminogen activation on cell surfaces. Distinct from this function, uPAR also modulates cell adhesion and migration on vitronectin-rich matrices. A...

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Detalhes bibliográficos
Main Authors: Gårdsvoll, Henrik, Jacobsen, Benedikte, Kriegbaum, Mette C., Behrendt, Niels, Engelholm, Lars, Østergaard, Søren, Ploug, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190949/
https://ncbi.nlm.nih.gov/pubmed/21799009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.220087
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