A Composite Role of Vitronectin and Urokinase in the Modulation of Cell Morphology upon Expression of the Urokinase Receptor

The urokinase receptor, urokinase receptor (uPAR), is a glycosylphosphatidylinositol-anchored membrane protein engaged in pericellular proteolysis and cellular adhesion, migration, and modulation of cell morphology. A direct matrix adhesion is mediated through the binding of uPAR to vitronectin, and...

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Bibliographic Details
Main Authors: Hillig, Thore, Engelholm, Lars H., Ingvarsen, Signe, Madsen, Daniel H., Gårdsvoll, Henrik, Larsen, Jørgen K., Ploug, Michael, Danø, Keld, Kjøller, Lars, Behrendt, Niels
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Mechanisms of Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258879/
https://ncbi.nlm.nih.gov/pubmed/18362146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C700214200
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