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Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide

We report the crystal structure of a soluble form of human urokinase-type plasminogen activator receptor (uPAR/CD87), which is expressed at the invasive areas of the tumor-stromal microenvironment in many human cancers. The structure was solved at 2.7 Å in association with a competitive peptide inhi...

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Detalhes bibliográficos
Main Authors: Llinas, Paola, Hélène Le Du, Marie, Gårdsvoll, Henrik, Danø, Keld, Ploug, Michael, Gilquin, Bernard, Stura, Enrico A, Ménez, André
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142576/
https://ncbi.nlm.nih.gov/pubmed/15861141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600635
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