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Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide
We report the crystal structure of a soluble form of human urokinase-type plasminogen activator receptor (uPAR/CD87), which is expressed at the invasive areas of the tumor-stromal microenvironment in many human cancers. The structure was solved at 2.7 Å in association with a competitive peptide inhi...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2005
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1142576/ https://ncbi.nlm.nih.gov/pubmed/15861141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600635 |
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