An Unbiased Approach To Identify Endogenous Substrates of “Histone” Deacetylase 8

[Image: see text] Despite being extensively characterized structurally and biochemically, the functional role of histone deacetylase 8 (HDAC8) has remained largely obscure due in part to a lack of known cellular substrates. Herein, we describe an unbiased approach using chemical tools in conjunction...

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Autors principals: Olson, David E., Udeshi, Namrata D., Wolfson, Noah A., Pitcairn, Carol Ann, Sullivan, Eric D., Jaffe, Jacob D., Svinkina, Tanya, Natoli, Ted, Lu, Xiaodong, Paulk, Joshiawa, McCarren, Patrick, Wagner, Florence F., Barker, Doug, Howe, Eleanor, Lazzaro, Fanny, Gale, Jennifer P., Zhang, Yan-Ling, Subramanian, Aravind, Fierke, Carol A., Carr, Steven A., Holson, Edward B.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201337/
https://ncbi.nlm.nih.gov/pubmed/25089360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500492r
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