Resultados da pesquisa - (( 3 nacl compared tran n.l ) OR ((( j tail clamp j new ) OR ( j nay comp can non ))))

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Mechanisms of block of a human cloned potassium channel by the enantiomers of a new bradycardic agent: S-16257-2 and S-16260-2.

Por Delpón, E., Valenzuela, C., Pérez, O., Franqueza, L., Gay, P., Snyders, D. J., Tamargo, J.
Publicado em 1996

“...1. The effects of S-16257-2 (S57) and S-16260-2 (R60), the two enantiomers of a new bradycardic...”
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Preliminary Characterization of Voltage-Activated Whole-Cell Currents in Developing Human Vestibular Hair Cells and Calyx Afferent Terminals

Por Lim, Rebecca, Drury, Hannah R., Camp, Aaron J., Tadros, Melissa A., Callister, Robert J., Brichta, Alan M.
Publicado em 2014

“... activating conductance, G (K,L). A similar current was first observed at 15 WG but remained relatively small...”
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Preoperative Diagnostic Angiogram and Endovascular Aortic Stent Placement for Appleby Resection Candidates: A Novel Surgical Technique in the Management of Locally Advanced Pancrea...

Por Trabulsi, N., Pelletier, J. S., Abraham, C., Vanounou, T.
Publicado no HPB Surg (2015)

“... margin may be gained, as the artery can be transected at its origin without the need for vascular clamp...”
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Voltage-dependent calcium and calcium-activated potassium currents of a molluscan photoreceptor.

Por Alkon, D L, Farley, J, Sakakibara, M, Hay, B
Publicado em 1984

“...Two-microelectrode voltage clamp studies were performed on the somata of Hermissenda Type B...”
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s-RT-MELT for rapid mutation scanning using enzymatic selection and real time DNA-melting: new potential for multiplex genetic analysis

Por Li, Jin, Berbeco, Ross, Distel, Robert J., Jänne, Pasi A., Wang, Lilin, Makrigiorgos, G. Mike
Publicado em 2007

“..., or for SNP discovery. GC-clamp-containing PCR products from interrogated and wild-type samples are hybridized...”
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Next-generation bis-locked nucleic acids with stacking linker and 2′-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes

Por Geny, Sylvain, Moreno, Pedro M. D., Krzywkowski, Tomasz, Gissberg, Olof, Andersen, Nicolai K., Isse, Abdirisaq J., El-Madani, Amro M., Lou, Chenguang, Pabon, Y. Vladimir, Anderson, Brooke A., Zaghloul, Eman M., Zain, Rula, Hrdlicka, Patrick J., Jørgensen, Per T., Nilsson, Mats, Lundin, Karin E., Pedersen, Erik B., Wengel, Jesper, Smith, C. I. Edvard
Publicado no Nucleic Acids Res (2016)

“... nucleobases, a new strategy previously not applied for any type of clamp-constructs. Although the Hoogsteen...”
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Chaperoning of a Replicative Polymerase onto a Newly-Assembled DNA-Bound Sliding Clamp by the Clamp Loader

Por Downey, Christopher D., McHenry, Charles S.
Publicado em 2010

“... onto DNA. We reveal a new role for a clamp loader: chaperoning of the replicative polymerase onto a...”
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Novel voltage clamp to record small, fast currents from ion channels expressed in Xenopus oocytes.

Por Taglialatela, M, Toro, L, Stefani, E
Publicado em 1992

“... noise (1 nA at 3 kHz), (b) control of the ionic composition of both the internal and external media, (c...”
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Steered molecular dynamics simulations on the "tail helix latch" hypothesis in the gelsolin activation process.

Por Cheng, Feng, Shen, Jianhua, Luo, Xiaomin, Jiang, Hualiang, Chen, Kaixian
Publicado em 2002

“...The molecular basis of the "tail helix latch" hypothesis in the gelsolin activation process has...”
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Pharmacological Properties and Functional Role of K(slow) Current in Mouse Pancreatic β-Cells: SK Channels Contribute to K(slow) Tail Current and Modulate Insulin Secretion

Por Zhang, Min, Houamed, Khaled, Kupershmidt, Sabina, Roden, Dan, Satin, Leslie S.
Publicado em 2005

“... the amplitude of K(slow) tail current in voltage-clamped mouse β-cells. K(slow) was also selectively...”
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Analysis of Damped Oscillations during Reentry: A New Approach to Evaluate Cardiac Restitution()

Por Munteanu, Adelina, Kondratyev, Aleksandar A., Kucera, Jan P.
Publicado em 2008

“...Reentry is a mechanism underlying numerous cardiac arrhythmias. During reentry, head-tail...”
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Effects of rupatadine, a new dual antagonist of histamine and platelet-activating factor receptors, on human cardiac Kv1.5 channels

Por Caballero, Ricardo, Valenzuela, Carmen, Longobardo, Mónica, Tamargo, Juan, Delpón, Eva
Publicado em 1999

“...1. The effects of rupatadine, a new dual antagonist of both histamine H(1) and platelet-activating...”
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Functional characterization and cold sensitivity of T1313A, a new mutation of the skeletal muscle sodium channel causing paramyotonia congenita in humans

Por Bouhours, Magali, Sternberg, Damien, Davoine, Claire-Sophie, Xavier, Ferrer, Willer, Jean Claude, Fontaine, Bertrand, Tabti, Nacira
Publicado em 2004

“... compared to wild-type. Deactivation from the open state assessed by the tail current decay was only slowed...”
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Quantitative analysis of tetrapentylammonium-induced blockade of open N-methyl-D-aspartate channels.

Por Sobolevsky, A I
Publicado em 2000

“...The blockade of open N-methyl-d-aspartate (NMDA) channels by tetrapentylammonium (TPentA...”
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A novel osmosensitive voltage gated cation current in rat supraoptic neurones

Por Liu, Xiao-Hong, Zhang, Wenbo, Fisher, Thomas E
Publicado em 2005

“... in part by a stretch-inactivated non-selective cation current that causes the cells to depolarize when...”
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Characterization of Erg K(+) Channels in α- and β-Cells of Mouse and Human Islets

Por Hardy, Alexandre B., Fox, Jocelyn E. Manning, Giglou, Pejman Raeisi, Wijesekara, Nadeeja, Bhattacharjee, Alpana, Sultan, Sobia, Gyulkhandanyan, Armen V., Gaisano, Herbert Y., MacDonald, Patrick E., Wheeler, Michael B.
Publicado em 2009

“.... Whole cell patch clamp recordings demonstrated the functional expression of Erg1 in α- and β-cells...”
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The Rickettsia Surface Cell Antigen 4 Applies Mimicry to Bind to and Activate Vinculin

Por Park, HaJeung, Lee, Jun Hyuck, Gouin, Edith, Cossart, Pascale, Izard, Tina
Publicado em 2011

“...-helix bundle head domain (Vh1) displaces intramolecular interactions with the vinculin tail domain...”
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The mechanosensitive channel of small conductance (MscS) functions as a Jack-In-The Box

Por Malcolm, Hannah R., Blount, Paul, Maurer, Joshua A.
Publicado no Biochim Biophys Acta (2014)

“... of these residues was mutated to alanine and leucine to modulate their hydrophobic interaction with the lipid tail...”
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Second coiled-coil domain of KCNQ channel controls current expression and subfamily specific heteromultimerization by salt bridge networks

Por Nakajo, Koichi, Kubo, Yoshihiro
Publicado em 2008

“... clamp revealed that homotetrameric KCNQ3 TCC2 is a negative regulator of current expression...”
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On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts

Por Iachettini, Sara, Stevens, Malcolm FG, Frigerio, Mark, Hummersone, Marc G, Hutchinson, Ian, Garner, Thomas P, Searle, Mark S, Wilson, David W, Munde, Manoj, Nanjunda, Rupesh, D’Angelo, Carmen, Zizza, Pasquale, Rizzo, Angela, Cingolani, Chiara, De Cicco, Federica, Porru, Manuela, D’Incalci, Maurizio, Leonetti, Carlo, Biroccio, Annamaria, Salvati, Erica
Publicado em 2013

“... of the hERG tail current tested in a patch clamp assay. Two related pentacyclic structures, the acetylamines...”
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