Synthesis and characterization of oligodeoxyribonucleotides modified with 2′-thio-2′-deoxy-2′-S-(pyren-1-yl)methyluridine

por Anderson, Brooke A., Hrdlicka, Patrick J.
Publicado en Bioorg Med Chem Lett (2015)

Merging Two Strategies for Mixed-Sequence Recognition of Double-Stranded DNA: Pseudocomplementary Invader Probes

por Anderson, Brooke A., Hrdlicka, Patrick J.
Publicado en J Org Chem (2016)

Mixed-Sequence Recognition of Double-Stranded DNA Using Enzymatically Stable Phosphorothioate Invader Probes

por Anderson, Brooke A., Karmakar, Saswata, Hrdlicka, Patrick J.
Publicado en Molecules (2015)

Synthesis and Characterization of Oligodeoxyribonucleotides Modified with 2′-Amino-α-L-LNA Adenine Monomers: High-affinity Targeting of Single-Stranded DNA

por Andersen, Nicolai K., Anderson, Brooke A., Wengel, Jesper, Hrdlicka, Patrick J.
Publicado 2013

Synthesis of Fluorescence Turn-On DNA Hybridization Probe using the (DEA)tC 2’-deoxycytidine Analogue

por Turner, M. Benjamin, Anderson, Brooke A., Samaan, George N., Coste, Michael, Burns, Dillon D., Purse, Byron W.
Publicado en Curr Protoc Nucleic Acid Chem (2018)

High-affinity DNA-targeting using Readily Accessible Mimics of N2′-Functionalized 2′-Amino-α-L-LNA

por Karmakar, Saswata, Anderson, Brooke A., Rathje, Rie L., Andersen, Sanne, Jensen, Troels B., Nielsen, Poul, Hrdlicka, Patrick J.
Publicado 2011

C5-Alkynyl-Functionalized α-L-LNA: Synthesis, Thermal Denaturation Experiments and Enzymatic Stability

por Kumar, Pawan, Baral, Bharat, Anderson, Brooke A., Guenther, Dale C., Østergaard, Michael E., Sharma, Pawan K., Hrdlicka, Patrick J.
Publicado 2014

Optimized DNA-targeting using triplex forming C5-alkynyl functionalized LNA

por Sau, Sujay P., Kumar, Pawan, Anderson, Brooke A., Østergaard, Michael E., Deobald, Lee, Paszczynski, Andrzej, Sharma, Pawan K., Hrdlicka, Patrick J.
Publicado 2009

Invader probes: harnessing the energy of intercalation to facilitate recognition of chromosomal DNA for diagnostic applications

por Guenther, Dale C., Anderson, Grace H., Karmakar, Saswata, Anderson, Brooke A., Didion, Bradley A., Guo, Wei, Verstegen, John P., Hrdlicka, Patrick J.
Publicado en Chem Sci (2015)

Synthesis and Biophysical Properties of C5-Functionalized LNA (Locked Nucleic Acid)

por Kumar, Pawan, Østergaard, Michael E., Baral, Bharat, Anderson, Brooke A., Guenther, Dale C., Kaura, Mamta, Raible, Daniel J., Sharma, Pawan K., Hrdlicka, Patrick J.
Publicado 2014

Optimization of Replication, Transcription, and Translation in a Semi-Synthetic Organism

por Feldman, Aaron W., Dien, Vivian T., Karadeema, Rebekah J., Fischer, Emil C., You, Yanbo, Anderson, Brooke A., Krishnamurthy, Ramanarayanan, Chen, Jason S., Li, Lingjun, Romesberg, Floyd E.
Publicado en J Am Chem Soc (2019)

Nanopore sequencing of an expanded genetic alphabet reveals high-fidelity replication of a predominantly hydrophobic unnatural base pair

por Ledbetter, Michael P., Craig, Jonathan M., Karadeema, Rebekah J., Noakes, Matthew T., Kim, Hwanhee C., Abell, Sarah J., Huang, Jesse R., Anderson, Brooke A., Krishnamurthy, Ramanarayanan, Gundlach, Jens H., Romesberg, Floyd E.
Publicado en J Am Chem Soc (2020)

Identification and characterization of 2(nd) generation Invader Locked Nucleic Acids (LNAs) for mixed-sequence recognition of double-stranded DNA

por Sau, Sujay P., Madsen, Andreas S., Podbevsek, Peter, Andersen, Nicolai K., Kumar, T. Santhosh, Andersen, Sanne, Rathje, Rie L., Anderson, Brooke A., Guenther, Dale C., Karmakar, Saswata, Kumar, Pawan, Plavec, Janez, Wengel, Jesper, Hrdlicka, Patrick J.
Publicado 2013

Next-generation bis-locked nucleic acids with stacking linker and 2′-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes

por Geny, Sylvain, Moreno, Pedro M. D., Krzywkowski, Tomasz, Gissberg, Olof, Andersen, Nicolai K., Isse, Abdirisaq J., El-Madani, Amro M., Lou, Chenguang, Pabon, Y. Vladimir, Anderson, Brooke A., Zaghloul, Eman M., Zain, Rula, Hrdlicka, Patrick J., Jørgensen, Per T., Nilsson, Mats, Lundin, Karin E., Pedersen, Erik B., Wengel, Jesper, Smith, C. I. Edvard
Publicado en Nucleic Acids Res (2016)