Identification and characterization of 2(nd) generation Invader Locked Nucleic Acids (LNAs) for mixed-sequence recognition of double-stranded DNA

Development of synthetic agents that recognize double-stranded DNA (dsDNA) is a long-standing goal that is inspired by the promise for tools that detect, regulate and modify genes. Progress has been made with triplex-forming oligonucleotides, PNAs, and polyamides, but substantial efforts are current...

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Main Authors: Sau, Sujay P., Madsen, Andreas S., Podbevsek, Peter, Andersen, Nicolai K., Kumar, T. Santhosh, Andersen, Sanne, Rathje, Rie L., Anderson, Brooke A., Guenther, Dale C., Karmakar, Saswata, Kumar, Pawan, Plavec, Janez, Wengel, Jesper, Hrdlicka, Patrick J.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833467/
https://ncbi.nlm.nih.gov/pubmed/24032477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo4015936
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