Loading...
Optimized DNA-targeting using triplex forming C5-alkynyl functionalized LNA
Triplex forming oligonucleotides (TFOs) modified with C5-alkynyl functionalized LNA (locked nucleic acid) monomers display extraordinary thermal affinity toward double stranded DNA targets, excellent discrimination of Hoogsteen-mismatched targets, and high stability against 3′-exonucleases.
Na minha lista:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2846108/ https://ncbi.nlm.nih.gov/pubmed/19885469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b917312a |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|