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C5-Alkynyl-Functionalized α-L-LNA: Synthesis, Thermal Denaturation Experiments and Enzymatic Stability

[Image: see text] Major efforts are currently being devoted to improving the binding affinity, target specificity, and enzymatic stability of oligonucleotides used for nucleic acid targeting applications in molecular biology, biotechnology, and medicinal chemistry. One of the most popular strategies...

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Detalhes bibliográficos
Main Authors: Kumar, Pawan, Baral, Bharat, Anderson, Brooke A., Guenther, Dale C., Østergaard, Michael E., Sharma, Pawan K., Hrdlicka, Patrick J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049248/
https://ncbi.nlm.nih.gov/pubmed/24797769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo5006153
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